Overview of Research

INSPIRE Therapy
Destroying inoperable tumors using pulsed electric fields

Electrical Cell Sorting
Identifying and isolating rare cells from blood to detect cancer before it becomes symptomatic

Developing new materials from the bottom up using biology to fabricate  nano-structures and electric fields to manipulate the nano-archetecture

Therapeutic Imaging
Developing new ways to monitor electric field mediated therapies
Imaging deeper into tissue with higher contrast than possible using light or acoustics
News
The lab has moved the UNC-NCSU Joint Department of Biomedical Engineering!!
New opening - Post-doctoral scholar: Interested BME / Biology / Electrical Engineering candidates should apply via email
New opening - Laboratory Technician: Interested candidates with a BS in Biology or BME should apply via email

"Burst and Continuous High Frequency Irreversible Electroporation Protocols Evaluated in a Three Dimensional Tumor Model" has been accepted for publication in Physics in Medicine and Biology
[In Press]

"Optimization of a Single Insertion Electrode Array for the Creation of Clinically Relevant Ablations Using High-Frequency Irreversible Electroporation" has been accepted for publication in Computers in Biology and Medicine
[Download] [Supplemental Material]

"Reduction of Muscle Contractions during Irreversible Electroporation Therapy Using High Frequency Bursts of Alternating Polarity Pulses" has been accepted for publication in the Journal of Vascular and Interventional Radiology (JVIR)
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"Treatment of Cancer In Vitro Using Radiation and High-Frequency Bursts of Submicrosecond Electrical Pulses" has been accepted for publication in the IEEE Transactions on Biomedical Engineering
[Download] [View Online] [Supplemental Material]

"A Comprehensive Characterization of Parameters Affecting High-Frequency Irreversible Electroporation Lesions" has been accepted for publication in the Annals of Biomedical Engineering
[Download] [View Online] [Supplemental Material]
Electroporation of cells in-vitro

 "Asymmetric Waveforms Decrease Lethal Thresholds in High Frequency Irreversible Electroporation Therapies" has been accepted for publication in Nature Scientific Reports
[Download] [View Online] [Supplemental Materials]
 Creation of spherical ablations using a single electrode and grounding pad "Production of Spherical Ablations using Non-Thermal Irreversible Electroporation - A Laboratory Investigation Using a Single Electrode and Grounding Pad" has been accepted for publication in the Journal of Vascular and Interventional Radiology  (JVIR) 
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Selective Ablation of Cancer Cells
 "Targeted Cellular Ablation Based On The Morphology of Malignant Cells" has been accepted for publication in Nature Scientific Reports
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INSPIRE Therapy
 "Bursts of Microsecond Pulses Inhibit Tumor Growth" has been accepted for publication in Nature Scientific Reports
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